China: scientists find promising oral COVID-19 treatment
shahennews
A new study led by Chinese university scientists has identified a compound derived from the antiviral drug “remdesivir” that exhibits potential as an oral treatment for COVID-19.
Published in the journal Science Translational Medicine, the study shows that ATV006, which was synthesized from the remdesivir derivative GS-441524, demonstrated improved oral absorption and robust antiviral efficacy against SARS-CoV-2 and variants in animal tests.
According to previous studies, GS-441524, though effective against SARS-CoV-2, suffers from poor oral bioavailability, which hampers its further development as an oral drug.
In the study, scientists found the oral administration of ATV006 can reduce viral loads, alleviate lung damage and effectively prevent death in infected mice.
//Petra// RZ
